By what day range does the third (proliferative) phase of wound healing begin?

By what day range does the third (proliferative) phase of wound healing begin?

• A. 1-3 days
• B. 5-20 days
• C. 30-40 days
• D. 60-90 days

Answer: (B)

The proliferative phase begins after the initial inflammatory response and is driven by active fibroblast remodeling, new blood vessel growth, and formation of granulation tissue. This stage also includes collagen deposition and the start of epithelialization to cover the wound. It typically starts around day 5 and can continue for about 2 to 3 weeks, roughly up to day 20. So the 5–20 days window best fits this phase. The earlier window (1–3 days) is the inflammatory phase, while the later ranges (30–40 days and 60–90 days) correspond to remodeling and maturation, when collagen is reorganized and wound strength gradually increases.

The proliferative phase begins after the initial inflammatory response and is driven by active fibroblast remodeling, new blood vessel growth, and formation of granulation tissue. This stage also includes collagen deposition and the start of epithelialization to cover the wound. It typically starts around day 5 and can continue for about 2 to 3 weeks, roughly up to day 20. So the 5–20 days window best fits this phase. The earlier window (1–3 days) is the inflammatory phase, while the later ranges (30–40 days and 60–90 days) correspond to remodeling and maturation, when collagen is reorganized and wound strength gradually increases.